Dr. Fisher is the President of the "P Less Than" Company, a consultancy.
He assists pharma companies with clinical and regulatory strategies and
conducts pharmacokinetic/pharmacodynamic analyses. Through 2000 Dr. Fisher
was Professor of Anesthesia and Pediatrics at the University of California
San Francisco and an Editor of the journal Anesthesiology, and an academic
colleague of Professors Lewis Sheiner and Stuart Beal. Between 2000 and 2003,
he was Vice President for Medical Affairs at DURECT, an ALZA spin-off. In 2003,
he resumed consulting full-time.
Dr. Shafer is Professor of Anesthesiology at Columbia University, Adjunct Professor
of Anesthesia at Stanford University, and Adjunct Professor of Bioengineering and
Therapeutic Sciences at UCSF. His research interests are in the mathematical modeling of
intravenous and inhalational anesthetics, including population PK/PD, drug interactions,
computer controlled drug administration, quantitative measures of anesthetic drug
effect, and model-based pharmaceutical development. He is Editor-in-Chief of Anesthesia &
Analgesia, and on the Editorial Boards of the British Journal of Anaesthesia and the Journal of Anesthesia.